Gene Symbol
FMR1
NCBI Gene ID
2332
Application
WB; IHC; IF; Functional Assay
Other Names
POF
FMRP
POF1
FRAXA
1×10^6 cells/vial
USD
Gene Description

The protein encoded by this gene binds RNA and is associated with polysomes. The encoded protein may be involved in mRNA trafficking from the nucleus to the cytoplasm. A trinucleotide repeat (CGG) in the 5' UTR is normally found at 6-53 copies, but an expansion to 55-230 repeats is the cause of fragile X syndrome. Expansion of the trinucleotide repeat may also cause one form of premature ovarian failure (POF1). Multiple alternatively spliced transcript variants that encode different protein isoforms and which are located in different cellular locations have been described for this gene. [provided by RefSeq, May 2010]

Quality control
>95% viability before freezing. All cells were tested and found to be free of mycoplasma, bacterial, viruses, and other toxins.
Components
1 vial of knockout cell line
Parental Cell Line
293T
Storage
Store at -80 centigrade upon receiving. Liquid nitrogen for a long-term storage. Minimizing freeze- thaw cycles.