Gene Symbol
NEFM
NCBI Gene ID
4741
Application
WB; IHC; IF; Functional Assay
Other Names
NFM
NEF3
NF-M
1×10^6 cells/vial
USD
Gene Description

Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and functionally maintain neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the medium neurofilament protein. This protein is commonly used as a biomarker of neuronal damage. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Oct 2008]

Quality control
>95% viability before freezing. All cells were tested and found to be free of mycoplasma, bacterial, viruses, and other toxins.
Components
1 vial of knockout cell line
Parental Cell Line
293T
Storage
Store at -80 centigrade upon receiving. Liquid nitrogen for a long-term storage. Minimizing freeze- thaw cycles.
Sequencing
1 bp insertion in exon 2
Insertion of the selection cassette in exon 2